Enostim logo

The natural male enhancer

Enostim, natural enhancer for men

EnoSTIM™ is a unique and proprietary formulation of active ingredients, apple and grape polyphenols (Nexira’s Proprietary Formulation), enriched with saffron. *

 3 synergistic benefits

  • Efficient blood flow enhancer: ENOs (endothelial Nitric Oxide synthase) synthetises NO which is directly implicated in blood flow. In vitro (1) and ex vivo (2) studies showed that Nexira’s proprietary formulation activates eNOs, which can increase blood flow up to 50%.
  • Saffron benefits: Saffron (flower stigmas from Crocus sativus) has been used in traditional medicine as an aphrodisiac.
  • Nitric Oxide protection: Nitric oxide has a short lifespan and is easily degraded by superoxide free radical. As shown in an in vivo study (3), the antioxidant molecules in Nexira’s Proprietary Formulation scavenge free radicals thereby protecting NO action and decreasing oxidative stress by 74%.


Results on Human

The latest 4 week-study was conducted on 94 men aged 45+ (4). Results, assessed by wildly accepted questionnaires (EHS and IIEF-5), are exceptional:

  • 74% of volunteers improved their hardness score (EHS)
  • 72% of consumers have a better IIEF-5 score
  • 71% would recommend EnoSTIM™ in the satisfaction survey

 

Directions of use: 300-600 mg / day

EHS Enostim


(1) Effect of NPF on the activation of eNOs through the phosphorylation of “Serine 1177” from endothelial cells (HUVECs) as measured by flow cytometry. 2008.

(2) NPF stimulate endothelial-dependent vasodilation by nitric oxide synthesis. Ex vivo study on rat aorta. 2004.

(3) The effects of NPF, a formulation containing grape and apple extracts and its effect on the production of peroxinitrites in hamsters subjected to aerobic physical activity. 2004

 

(4) CEN Nutriments, 2017

·        Efficient blood flow enhancer: ENOs (endothelial Nitric Oxide synthase) synthetises NO which is directly implicated in blood flow. In vitro (1) and ex vivo (2) studies showed that Nexira’s proprietary formulation activates eNOs, which can increase blood flow up to 50%. 

·        Saffron benefits: Saffron (flower stigmas from Crocus sativus) has been used in traditional medicine as an aphrodisiac. 

·        Nitric Oxide protection: Nitric oxide has a short lifespan and is easily degraded by superoxide free radical. As shown in an in vivo study (3), the antioxidant molecules in Nexira’s Proprietary Formulation scavenge free radicals thereby protecting NO action and decreasing oxidative stress by 74%.