• Proven reduction of stress manifestations
  • Mental & emotional well-being activator
  • Organic certified

Serenzo TM is a safe and effective food supplement ingredient for stress relief and well-being improvement. It comes from specific varieties of citrus fruits.


The move toward holistic health is creating new opportunities for Nutraceuticals to balance emotional well-being and support mental health. 

Serenzo TM is a safe and effective food supplement ingredient for stress relief and well-being improvement. Sourced from 100% botanical origin (Citrus sinensis essential oil microencapsulated with acacia gum), Serenzo™ is certified organic and well tolerated. 

Mood, cognition, anxiety, emotion and other psychological behaviors are regulated by numerous neurotransmitters. Two of them are particularly involved in stress regulation: Dopamine (stress activator) and Adenosine (stress regulator). Acting at the neuronal level, Serenzo TM has exceptional properties:

  • Identification of Serenzo TM as Adenosine
  • Activation of the stress regulation
  • Inhibition of the stress response receptor

Stress manifestation decrease

Serenzo TM was evaluated in an open clinical trial for 12 weeks1. The efficacy was assessed using normative psychological questionnaires2 and a physiological marker. The first benefits were demonstrated after only 6 weeks:

  • 50% reduction of subjective feeling of stress
  • 53% reduction of global stress, measured through normative questionnaire

NEW – Improvement of Mood and Emotional well-being

In 2022, the new Serenzo™ consumer study conducted on 134 consumers showed a significant improvement on mental load and a significant boost of emotional well-being (assessed via DASS score variation) through time but not for placebo3,4

Learn more in our dedicated blog post!

Serenzo TM is a natural ingredient used in food supplements.

  • Organic grade available
  • Low use level
  • Manufactured in France

According to Innova Market Insights, there has been a 26% increase in supplement launches over the past five years (Oct 2017 – Sep 2022). After immune health, the second most launched claim is brain-mood health with +25%.

Learn more about the mental health market and discover the new consumer study conducted by Nexira.


infographic mental health


serenzo ingredient
orange nexira

I am interested in Serenzo TM, please contact me.


(1) Observational study: Assessment of benefit and tolerability of SerenzoTM in chronically stressed subjects. Open-label, pilot monocentric study. 2012
(2) Symptom Check List 90 R, Hamilton Anxiety Scale, Screening Scale of Chronic Stress
(3) Normalized self-reported Perceived Stress Scale (PSS-10)
(4) Normalized self-reported DASS-12
This communication is not intended to the final consumer. It provides scientific information for professionals only. Communications to the final consumer have to be checked according to local regulations in force, since the conditions of use are beyond our control. This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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