Nexira provides innovative natural ingredients, sustainably sourced in a responsible way, to improve health and well-being. Our health portfolio includes premium nutraceuticals, a complete palette of innovative Hero ingredients : strongly supported active ingredients either with scientific and clinical evidence, marketing support or robust sourcing storytelling. We also provide distinctive and comprehensive botanical extracts range backed with Nexira’s best and reputable quality guarantees.
In order to meet the requirements of an increasingly demanding market when it comes to efficiency and innovation, Nexira has conducted extensive research work in the field of weight management and offers a comprehensive range of healthy ingredients originating from diverse natural sources.
Prebiotic - Fiber Enrichment
Very early in its history, Nexira began to focus its scientific research on the nutritional benefits of acacia as a native source of soluble dietary fiber. With a minimum of 90% fiber content guaranteed on dry weight, acacia fiber is the ideal clean label ingredient for fiber fortification.
Numerous studies have been performed and the acacia prebiotic effect has been largely demonstrated. Nexira has developed different references with specific certifications, such as organic and synergies for example with Baobab fiber. Our range of fibers is easy to use in a large array of nutritional applications to formulate healthy, natural and organic products.
Gut - Liver
With a rising awareness of the importance of gut and liver health for overall body function, consumers are turning to products and ingredients that promote a balanced gut microbiome and support optimal liver function.
From natural branded ingredient to botanical extracts, Nexira a diverse range of solutions to meet these growing needs.
Sport - Mobility
All athletes are looking for the same thing: effective, natural ingredients to improve their performance. Discover our wide portfolio of clinically proven, functional ingredients to meet consumers’ demands. The aging population in developed countries is increasingly on the lookout for well-being and healthy-aging solutions. Conscious about the type of ingredients used in their food, they are looking for plant-based herbal ingredients to answer their joint health concerns.
Cognition
The brain health supplement market is predicted to surge with the increased aging population. Leveraging its formulation expertise and dose design capabilities, Nexira has developed a unique natural combination for cognitive performance.
Urinary comfort
Nexira has built a globally recognized reputation for reliability and quality in the world of plant-based dietary supplements for women health.
Hormonal balance
Coming soon…
Vitality
The global energy supplements market is expected to grow due to increasing demand by busy professional life, on-the-go parents and active seniors looking for more energy to meet their daily needs.
Mood
In today’s fast-paced world, stress can negatively impact daily life. Nexira offers safe and effective ingredients sourced from botanical origin for stress and well-being.
Sexual Health
Nexira has developed a unique combination of premium extracts to offer a natural solution that can enhance male performance.
Immunity
There is an increasing awareness of the impact of food consumption on our health and consumers are now tending to a preventive approach to strengthen their health. Nexira offers botanical extracts to naturally boost the immune system.
Beauty from within
Nutricosmetic is the point at which nutrition and cosmetics meet. The term encompasses the beneficial effects on beauty resulting from consuming nutrients through the use of food supplements. Nexira is inspired by nature to offer a relevant response to consumer demand for the use of food supplements to enhance beauty from within.
The NutriBeauty range addresses the main market segments, for the development of new products: Glow & Beauty for Skin Care, Youth & Prevention for Anti-aging and Hair & Nails Care.
Cardio - Blood sugar
In addition to a well-balanced diet and regular exercise, certain specific natural solutions can also be helpful for cardiovascular health. Nexira offers natural ingredients sourced from diverse botanical origins for heart health.
EMPOWER A HEALTHIER MICROBIOME
Premium
inavea CAROB ACACIA
Empower a healthier microbiome
Complementarity of Carob & Acacia fibers
Boosted microbiota diversity
Carbon neutral, organic
Complementarity of Carob & Acacia fibers
Boosted microbiota diversity
Carbon neutral, organic
inavea™ CAROB & ACACIA is an all-natural and complementary formulation of Carob and Acacia fibers, bringing respectively galactomannan and arabinogalactan polysaccharides.
Acacia and Carob are sustainably sourced in Africa and Mediterranean countries and organic certified. inavea™ CAROB & ACACIA provides a high fiber content and prebiotic activities leading to a boosted microbiome diversity.
In a recent ex vivo study mimicking the intestinal system, acacia and carob fibers alone have demonstrated significant prebiotic activities. At the equivalent of 5g/day, inavea™ CAROB & ACACIA has shown a prebiotic effect and a complementarity on microbiota diversity.
To empower a healthier microbiome, this new reference boosts the microbiota diversity, ie the number of different species of bacteria in the gut microbiome. Evaluated by the CMS, an innovative Community Modulation Score, the microbiota diversity has been improved by inavea™ CAROB & ACACIA with more than 29 species being promoted.
inavea™ CAROB & ACACIA has demonstrated a microbiota modulation with the promotion of beneficial bacteria and Short Chain Fatty Acids. Thanks to the different structure of acacia and carob fibers, inavea™ carob & acacia offers a full spectrum fermentation, acting across the entire intestine.
inavea TM CAROB & ACACIA is ideal to fortify nutritional powders, functional snacks and shots.
100 % all-natural & appealing combination
Acacia and carob are confirmed dietary fibers by the FDA
Carbon neutral footprint, organic
inavea™ CINNAMON ACACIA is an all-natural and organic synergistic formulation of Cinnamon & Acacia, two African treasures with a long history within Nexira’s portfolio.
Providing prebiotic fibers from Acacia and polyphenols (including PACs) from Cinnamon, inavea™ CINNAMON ACACIA perfectly illustrates Nexira’s expertise in microbiome modulation.
In a recent in vivo study mimicking the conditions of dysbiosis-induced by a high fat high sucrose (HFHS) diet, inavea™ CINNAMON ACACIA has proven a strong prebiotic activity, a synergistic contribution to balance the gut microbiome and a significant role in metabolic heath improvement.
Our study has demonstrated the complementary & significant prebiotic activity of inavea™ CINNAMON ACACIA:
• Significant ability to modulate overall gut microbiota population
• Increase of SCFA propionate and butyrate production (1)
• Promotion of beneficial bacteria, such as Parabacteroides distasonis, which benefits on metabolic health markers such as glycemia and
weight have been substantiated (Wang et al, 2019)
inavea TM CINNAMON ACACIA is suitable in a wide range of dietary supplement applications and functional food & beverages:
[applications]
100 % all-natural & appealing combination
Subtle taste of Cinnamon
High fiber content**
Carbon neutral footprint
Inavea™ BAOBAB ACACIA is an all-natural and organic synergistic formulation of Baobab & Acacia, two African treasures with a unique sustainability commitment. inavea™ BAOBAB ACACIA offers a proven prebiotic effect at 5g/d which contribute to the balance of microflora for enhanced digestive health and general well-being.
Baobab pulp and Acacia have been traditionally consumed for centuries for their wide range of nutritional and medicinal properties. Nexira’s new proprietary study, using the SHIME® model[1], has demonstrated for the first time the prebiotic effects of Baobab at 10g/d and the synergistic prebiotic effect of inavea™ BAOBAB ACACIA at 5g/d.
Learn about our involvement in the sustainable development and preservation of the natural baobab and acacia materials we source. inavea™ has proudly achieved carbon neutrality, ensuring a real reduction in greenhouse gas emissions and supporting the UN Sustainable Development Goals (SDGs) and many co-benefits for both local communities and the environment. Learn more about Nexira’s whole carbon neutrality approach.
Performing formulation, inavea™ BAOBAB ACACIA acts as a friendly microflora regulator effective in creating, restoring and sustaining the beneficial balance. Our proprietary scientific study has demonstrated the complementary & significant prebiotic activities of inavea™ BAOBAB ACACIA.
The study has also demonstrated a gradual fermentation across the entire intestine, i.e. a full spectrum gut fermentation. inavea™ BAOBAB ACACIA is suitable for a low FODMAP diet.
inavea™ BAOBAB ACACIA health benefits are multiple:
• Balanced microbiota to boost beneficial bacteria
• Enhanced digestive health
• Supported metabolic health with modulation of oxidative
and inflammatory markers
100 % all-natural & appealing combination
Subtle flavor of Baobab, slightly tangy with fruity notes
Low hygroscopicity
High nutrient content
Carbon neutral footprint
As the world leader in acacia, we are aware of our responsibility. inavea TM is the first premium brand of organic and sustainable ingredients preserving natural resources, supporting local communities and offering a carbon neutral footprint.
inaveaTM PURE ACACIA is an all-natural, organic and GMO-free prebiotic ingredient sourced from carefully selected acacia trees. inavea TM PURE ACACIA offers a unique sustainable commitment and the value of high digestive tolerance for fiber enrichment* and prebiotic properties in a large array of applications.
inavea™ has proudly achieved carbon neutrality, ensuring a real reduction in greenhouse gas emissions and supporting the UN Sustainable Development Goals (SDGs) and many co-benefits for both local communities and the environment. Learn more about Nexira’s whole carbon neutrality approach.
We are proud to announce that inavea™ has been selected as a finalist of the 2021 World Food Innovation Awards in the Sustainability category.
inavea TM PURE ACACIA is the ideal clean label ingredient for fiber fortification* and prebiotic claims.
Prebiotic effect of acacia fiber has been largely demonstrated for 40 years in more than 40 studies. inavea TM PURE ACACIA has a strong prebiotic effect at a dose of 10 g/day, stimulating healthy bacteria and contributing to the Short Chain Fatty Acids production.
Our latest study, using the SHIME model, has demonstrated an increase of microbiota diversity (healthy marker) thanks to our prebiotic acacia intake.
Previous studies have demonstrated that inaveaTM PURE ACACIA helps to restore the gut barrier.
inavea TM PURE ACACIA offers the value of a clean label in addition to the consumer appeal of 100% vegetable origin and fiber enrichment.
inavea TM PURE ACACIA offers distinctive and proven health benefits for all nutritional foods & beverages
Only Organic grade available
GMO-free
Carbon neutral footprint
Manufactured in France
100 % soluble / good dispersibility
Odorless / colorless / tasteless
Low viscosity / low hygroscopicity
Low-carb / low caloric value
Excellent stability to extreme process storage conditions
cognition cognitive
brain
Red Ginseng root (Panax ginseng C.A. Meyer)(Araliaceae family), is sourced from five-year-old plants from Jilin, a northeastern province of China.
Ginsenosides, the active molecules from ginseng, are specific types of triterpene saponins. Ginsenosides are distributed in many parts of the ginseng plant, including the root and the leaf. Nexira has a high proficiency regarding the entire chain and guarantees the authenticity of our Red Ginseng root extract, without any adulteration with leaf or other species.
Nexira’s Ginseng Extract :
Strict raw material selection
Gentle process: Water extraction at our facility in France
Standardization to 5% total ginsenosides
In Asian traditional medicine, dried ginseng is used as a tonic to rejuvenate vital energy.
Ginseng contributes to the natural defenses and proper functioning of the immune system. At least 30 ginsenosides have been isolated and characterized in the literature. The physiological actions of individual ginsenosides may work in opposition. For example, the two main ginsenosides, Rb1 and Rg1, respectively, suppress and stimulate the central nervous system. These opposing actions may contribute to the «adaptogenic» description of ginseng and its purported ability to balance bodily functions. 1,2
Ginseng is traditionally used to enhance cognitive and physical abilities, in cases of weakness, tiredness or loss of concentration. Ginseng is also approved for use during convalescence. 1,3
Panax ginseng also benefits from several pending claims.
Thanks to its multiple health benefits and its notoriety as an adaptogen and a nootropic, Ginseng is a rising ingredient in Supplements & Beverages
Nutrigenomic Mechanism: Activation of Cell Defenses & Detoxification Pathway
Hepure is an organic and synergistic formulation of Clove and Immortelle extracts for a hepatoprotective and detoxifying action.
Immortelle (Helichrysum italicum), which comes from the rocky and sunny lands of the Corsican maquis in France, is also called Everlasting thanks to its exceptional longevity: its flowers never fade. Immortelle has been described in the literature for its antioxidant activity and its inflammatory marker modulation. 1,2,3
Clove (Syzygium aromaticum) has demonstrated its superiority in flavonoids content, antioxidant activity and its hepatoprotective effect. 4,5
Detox is a natural process that enables the neutralization and elimination of toxins. Liver allows the elimination of waste by transforming toxins and by a solubilization process, which require potent enzymatic cascade and can generate free radicals. Supporting antioxidant mechanism of the liver may be beneficial for detoxification process and hepatoprotection.
Starting with more than 100 botanical sources, Nexira compared antioxidant potency and nutrigenomic mechanism in liver cells through an extensive and innovative screening.
HEPURE has confirmed the best synergy in direct antioxidant activity and its superiority in increasing gene expression coding for antioxidant defenses by the liver cell (nutrigenomic mechanism). Thus, Hepure has proven a synergistic antioxidant activity in liver cells, the liver protection, a boost in antioxidant production, and a support to the detoxifying process.
Pending claim on Helichrysum italicum*: «Helps to maintain a healthy liver function, supporting the digestion and the body purification».
A detox cure can help contribute to digestive well-being, preserve the skin’s beauty, assist with weight loss, maintain energy and vitality, and strengthen the immune system.
Improvement of working memory & cognitive performances
Efficacy from single dose to prolonged use
cognition cognitive
brain
Cognivia TM is a vegetal nootropic, the first ingredient to combine Garden Sage leaf extract and Spanish Sage encapsulated essential oil for an enhanced efficacy.
Sage has been used for centuries for its multiple health benefits. This plant has been widely studied in the literature for its efficiency on cognitive performances. Clinical studies have established memory and alertness improvements related to the separate use of Spanish sage and Garden sage1,2,3,4,5.
Cognivia TM has been revealed as 2020 finalist for the NutraIngredients Awards (Europe & USA) in the Healthy aging category and Cognitive function category!
Nexira’s recent in vivo study shows the beneficial synergistic effect on long-term memory, in both single dose and prolonged use6. Cognivia TM demonstrated significant results compared to individual Sage sources.
Our in vivo study demonstrated that the mechanism of action of Cognivia TM is related to CamKII pathway.
Our first clinical study was conducted with Northumbria University on healthy active volunteers. Results, assessed by well-known COMPASS battery of cognitive tests, have demonstrated:
Overall benefit on working memory function
Increase of performance over time consumption
Efficacy from single intake to prolonged use
Our NEW placebo controlled, double-blind, randomized, crossover clinical study led by INSERM during intense physical activity has highlighted:
Acute Effect; Once again, Cognivia™ has been proven to be efficient from single intake.
Working Memory Boost; +9% increase in Numeric Working Memory!
Reaction Time Increase; Compared to placebo, Cognivia™ has demonstrated a systematic and overall significant decrease in Reaction Time throughout all test points, which could lead to higher attention performance for e-gaming.
Perceived Exertion Decrease; Cognitive tests were performed during intense physical activity. Workout has been felt as very intense and inducing fatigue. Cognivia™ has shown a significant overall decrease in Rate of Perceived Exertion compared to placebo.
Cognivia TM is easy to use as a food supplement ingredient for brain performance in capsule, tablet, stick pack, powder.
Organic grade available
Manufactured in France
Water-dispersible powder
Low level of use
Available pending claims on memory
With a high purity rate (60% nucleotides), and formulated on prebiotic acacia, Immunell TM contributes to reinforce immune response.
Naturally occurring in food and breast milk and found in all living cells of the body, nucleotides are semi-essential molecules. Nucleotides have been used for years in nutrition to support organ growth, immune system and intestinal function.
Being a unique source for the 4 semi-essential nucleotides Adenine, Cytosine, Guanine and Uracil, Immunell TM acts on these biological functions to improve general health.
Cellular turnover of immune and gastro-intestinal systems requires nucleotide. Immunell TM provides the nucleotides necessary to facilitate cellular regeneration through cell proliferation and tissue renewal.
Immunell TM stimulates specific internal defenses, accelerates and reinforces the immune response against external factors.
Immunell TM is the perfect immunity bodyguard manufactured in France.
Synergistic complex for Appetite control
- Latest innovation for appetite control
- Unique synergistic combination
- Patent-pending formulation
Carolean™, a synergistic formulation based on carob and nopal, is a proprietary patent-pending complex specifically designed for appetite control.
Sourcing
With over 20 years of experience and unrivalled expertise on sourcing and processing, Nexira has established a leading position with its star ingredient: Cactus on the weight management market.
Nexira has acquired a Swiss company, expert in carob processing. Carolean™ complex is the fruit of combined R&D efforts to design an innovative solution.
Carolean™ provides both effectiveness and convenience for appetite control. The new patent-pending ingredient has demonstrated a clear ability to reduce appetite and limit cravings.
In conditions mimicking the ingestion (Temperature, pH), Carolean™ shows a superior kinetic reaching the satiety culmination quicker when compared to recognized market standards. 15 minutes after ingestion, already 70% of the viscosity is reached which optimizes the satiety effect more rapidly.
Our unique proprietary process enables a large variety of powder quality and behavior which makes our complex notably effective at ambient temperature.
Carolean™ is suitable for food supplements.
Cactinea is a weight management ingredient derived from the cactus fruit of Opuntia ficus-indica, called prickly pear.
Nexira and Tunisian farmers maintain a long-term partnership which respects both organic rules and sustainable farming. Direct sourcing includes rigorous selection and gentle process. With almost 20 years of experience and unrivalled know-how on cactus, Nexira delivers a high-performance cactus fruit extract.
The prickly pear is considered as a superfruit. It is an extremely potent antioxidant with proven metabolic health benefits on cholesterol modulation, vascular oxidative status and inflammatory markers modulation1,2,3.
Traditionally, prickly pear infusions are known for their depurative and diuretic benefits4,5. Cactinea TM has clinically demonstrated exceptional water elimination properties.6
Cactinea TM has also proven its efficacy by improving body shape and reducing heavy leg and swollen sensations.
Cactinea TM is a nutraceutical ingredient used in functional beverages and food supplements.
Organic grade available
100% Soluble & Clear in solution
Microgranulated powder
Natural carrier: acacia gum
Beautiful color (pink to orange)
Exotic taste
VinOgrape™ Plus is a natural grape extract with proven prebiotic effect and acting on microbiome modulation.
Our range of Grape extracts results from the association of an exceptional “terroir” with thousands of years of agricultural expertise & specific extraction process. VinOgrape™ Plus is produced using a special making process which provides the highest level of total polyphenols.
The International Scientific Association for Probiotics and Prebiotics (ISAPP) defines a prebiotic as ‘a substrate that is selectively utilized by host microorganisms conferring a health benefit’1 and has officially recognized grape extract as a prebiotic.
A 5-weeks in vivo study on intestinal mucosa markers and fecal microbiota in induced gut dysbiosis conditions shows that VinOgrape™ Plus significantly modulates the gut microbiota profile vs control after gut dysbiosis induction.
VinOgrape™ Plus has shown a significant ability to increase the abundance of Akkermansia muciniphila, suggesting an active role in metabolic disorder as well as weight control.
VinOgrape™ Plus is suitable for food supplements.
Natural Cranberry extracts for urinary tract health
Organic cranberry extracts
Up to 90% fruits solids content
Up to 90% PACs content
Our plant, located in France and equipped with on-site laboratory, applies the most reliable methods of analysis for PACs content: BL-DMAC, Bate Smith (BS), HPLC. I
In order to ensure our products are derived from Vaccinium macrocarpon, Nexira has developed a proprietary universal method of analysis to guarantee the identity and the quality of ExocyanTM
Naturally packed with polyphenols and especially ProAnthoCyanidins (PACs), ExocyanTM has powerful antioxidant properties. Nexira offers the industry’s most extensive range of cranberry extracts, standardized in PACs (proanthocyanidins) or in fruits solids, by using pomace or juice (or in combination) with several processing options.
Nexira can produce cranberry extracts with extremely high levels of active compounds, such as 90% PACs by Bate-Smith and 20% PAC by BL-DMAC.
Cranberry extracts for urinary tract health: A-type PACs help to reduce the adhesion of E.coli bacteria on the urinary tract walls.
Since July 2020, the Food and Drug Administration authorizes qualified health claim for dietary supplements related to Cranberry and UTI. “Limited scientific evidence shows that consuming 500mg each day of cranberry dietary supplement, healthy women who have had a urinary tract infection, may reduce their risk of recurrent UTI.”
Exocyan™ 100% Whole Cranberry Powder (93002 available references: Exocyan™ 10G and Exocyan™ 10G Bio)
Meets the FDA qualified health claim at 500 mg
Cost-efficient
Organic grade available
ExocyanTM is a nutraceutical ingredient used in food supplements and functional beverages.
Organic grade available
Manufactured in France
Non-GMO sources
Available in solvent-free and organic grades.
The physical characteristics of Exocyan TM (water soluble, low hygroscopicity, direct compression etc.) make this range easy-to-use in a wide range of applications and use levels.
Can be used in a capsule, softgel, tablet, functional beverage, gum or stick pack.
FlexiGO TM is an all-natural solution of Devil’s claw extracts for joint health. FlexiGO TM helps to improve mobility, flexibility and joint comfort.
Manufactured in France, this ingredient, coming from a root growing only in the South of Africa, is the natural solution to improve joint health.
Nexira has established a long-term supply chain partnership throughout the industry. Once the roots are sustainably picked, they are carefully transported and processed in France using a gentle process with a water extraction and a physical concentration.
Harpagophytum procumbens D. and Harpagophytum zeyheri Decne also known as Devil’s Claw, are traditionally used to maintain joint health.
Harpagophytum has clinically proven effects on joint health1,2,3
Contributes to decrease inflammation markers
Improve mobility and flexibility.
This ingredient can be used for elder people and for athletes and active people.
FlexiGO TM is a nutraceutical ingredient used in food supplements.
Organic grade available
Manufactured in France,
Standardized concentrations of up to 20% of harpagoside monopic in HPLC method.
100% Devil’s Claw (carrier-free).
In Europe Harpagophytum procumbens benefits from two pending claims4
Helps to maintain joint health
Helps to maintain flexible joints and good mobility
Kosher certified and suitable for vegetarian & vegan
ID-alG TM is a brown seaweed extract derived from Ascophyllum nodosum and intended to help limit fat and sugar storage in the body and control weight.
Ascophyllum nodosum is a species of brown algae belonging to the Fucaceae family. It is often found along the rocky coasts of the North Atlantic, where it forms dense colonies. Measuring up to 1 meter 50, it is harvested manually all year round. After being carefully selected in the ocean, the long brown algae fronds are checked again in the local factory before the first processing stages.
Rich in marine polyphenols content that blocks the activity of the two main digestive enzymes, lipase and amylase, ID-alGTM is a weight-loss solution for women and more specifically for 45 years & over.
Thanks to its potent inhibition activity on lipases and on alpha-amylases, ID-alGTM reduces fats and carbs assimilation, inducing a reduction of the caloric intake for a global weight control effect. This inhibition activity of theses enzymes is guaranteed to overpass 50% (in tubo test).
The latest clinical study1 conducted with ID-alGTM confirms its outstanding weight management properties:
Significant weight loss correlated with fat mass
Decrease in fat assimilation lowering body fat mass and abdominal & visceral fat
Significant reduction in carbs assimilation, leading to a decrease in glycated hemoglobin (HbA1C)
Body shape improvement
No signs of discomfort
Nexira delivers a high-performance ingredient in weight management, approved by the general satisfaction of consumers2:
76% were convince of the weight management effect of ID-alG™
72% would continue using ID-alG™
ID-alG TM is a natural ingredient manufactured in France, used in food supplements.
Okralin TM is a 100% natural and patented fat binder for weight management, formulated with okra and inulin.
Okra is one of the oldest cultivated crops. Well-known, Okra is usually consumed as a vegetable in salad, soup or stew.
Nexira has full control over our supply of okra, from seed selection to final powder.
Grown in our partner plantations, the okra pods are carefully selected, hand-picked and gently processed into a fine powder.
Shipped to our manufacturing facilities in France, the okra is processed to obtain the exclusive and patented ingredient with a proprietary formulation we call OkralinTM.
Manufactured in France, 100% natural and vegan, Okralin TM has been awarded by NIE Magazine ingredient of the Year in the “Weight Maintenance” Category. The jury declared “Nexira has brought to market a product with the whole package: fully traceability, renewable plant-based source, preclinical and clinical data with meaningful endpoints. This is exactly the kind of ingredient the space needs to continue to build credibility and trust with consumers.
OkralinTM , the breakthrough fat binder, is the newest and the most powerful fat binder on the market.
Acting in the stomach, OkralinTM binds fats. The complex creates a gel that is naturally eliminated, reducing fat and calorie absorption.
Supported by a 12-week clinical study, strongly documented, OkralinTM showed amazing results on weight-loss for men and women, losing 4 times much weight than those on a healthy diet alone.
Acting on body fat mass reduction, hip and waist, 97% of consumers were satisfied by benefits.
The clinical study strengthens the impressive benefits and tolerability of OkralinTM.
OkralinTM is a nutraceutical ingredient used in food supplements.
EnoSTIM TM is a proprietary synergistic formulation of active ingredients, apple and grape polyphenols, enriched with saffron.
EnoSTIM TM has been awarded the Ingredient of the Year in the “Healthy Ageing” category.
Regarding EnoSTIM TM, judges declared
Sexual activity is an important indicator of the overall health and well-being of men.
Saffron (flower stigmas from Crocus sativus) has been used in traditional medicine as aphrodisiac. Saffron’s ability to improve male performance was demonstrated in several clinical studies1. In Europe, saffron benefits from the pending claim: “Improves erection and relaxes muscles”2.
The Nitric Oxide (NO) pathway is the cornerstone of the blood flow mechanism allowing penile erection. eNOs (endothelial Nitric Oxide synthase) synthetises NO, thereby directly relates to blood flow. In vitro3 and ex vivo4 studies showed that Nexira’s Proprietary Formulation activates eNOs, which can increase blood flow up to 50%. As shown in vivo5, Nexira’s proprietary formulation scavenge free radicals thereby protecting NO action and decreasing oxidative stress by 74%.
A 4-week study was conducted on men aged 45+6. On week 4, results are outstanding, assessed by wildly accepted questionnaires: 74% of volunteers improved their hardness score.
EnoSTIM TM is a nutraceutical used in food supplements.
Manufactured in France
Recommended use level: 300-600mg per day
Neopuntia TM is a natural weight management pure cactus powder. Neopuntia TM is a patented combination of insoluble and soluble dietary fibers.
Nexira and Tunisian farmers maintain a long-term partnership which respects both organic rules and sustainable harvesting of Opuntia ficus indica. Through its cactus sourcing, Nexira is involved in sustainable development via environmental, human and economic actions.
With over 20 years of experience and unrivalled expertise on cactus sourcing and processing, Nexira offers a standardized pure cactus leaf powder. Neopuntia TM is perfect for nutraceutical applications.
In vitro1 study, simulating gastrointestinal tract conditions, has demonstrated a reduction of fat absorption: 28% of ingested fat binds to Neopuntia TM while branded chitosan showed no effect.
A pilot clinical study2 has also demonstrated results on human: Neopuntia TM increases fat excretion by 27%.
Neopuntia TM absorbs fat and sugar3 and supports healthy weight management.
A published clinical study4 shows Neopuntia TM, consumed with a healthy diet, has positive effects on balancing blood lipids levels. Neopuntia TM helps to increase HDL cholesterol level.
39% of women studied no longer showed Syndrome X criteria using Neopuntia TM.
Three interventional studies in human demonstrated positive and significant glycaemia modulation5,6,7.
Neopuntia TM is a nutraceutical ingredient used in supplements and functional food.
Organic grade available
Pure cactus powder
Organic certified
Protection of LDL cholesterol
Guaranteed content in hydroxytyrosol
Oli-Ola TM is an organic certified olive extract containing olive polyphenols with approved health claim in Europe1.
Oli-Ola TM is a 100 % natural olive extract produced from organic agriculture, from a unique source of ancient olive trees in the Southern Mediterranean region.
They grow wild, allowing the highest content of hydroxytyrosol.
With more than a century of experience in manufacturing high quality ingredients, Nexira has developed a unique process that guarantees both the safety and the effectiveness of Oli-Ola TM.
Oli-Ola TM is an olive extract with a guaranteed level of hydroxytyrosol, a very potent form of polyphenol.
On April 8, 2011 the European Food Safety Authority (EFSA) stated the following positive opinion allowing the first health claim for olive polyphenols:
“The Panel concludes that a cause and effect relationship has been established between the consumption of olive polyphenols (standardized by the content of hydoxytyrosol and its derivatives) and protection of LDL particles from oxidative damage”.
This statement fully qualifies Oli-Ola TM hydroxytyrosol as an approved antioxidant for cardiovascular health1.
Oli-Ola TM is a natural ingredient suitable for food supplements.
Organic grade available
Manufactured in France
Proven reduction of stress manifestations
Acts at the neuron level
Organic certified
Serenzo TM is an all-natural ingredient to help stress management. It comes from specific varieties of citrus fruits.
In today’s fast-paced world, stress can negatively impact daily life. Mood, cognition, anxiety, emotion and other psychological behaviors are regulated by numerous neurotransmitters. Two of them are particularly involved in stress regulation: Dopamine (stress activator) and Adenosine (stress regulator). Serenzo TM is a safe and effective nutraceutical for stress and well-being.
Acting at the neuronal level, Serenzo TM has exceptional properties
Identification of Serenzo TM as Adenosine
Activation of the stress regulation
Inhibition of the stress response receptor
Serenzo TM was evaluated in an open clinical trial for 12 weeks. The efficacy was assessed using normative psychological questionnaires and a physiological marker. The first benefits were demonstrated after only 6 weeks:
50% reduction of subjective feeling of stress
53% reduction of global stress, measured through normative questionnaire
Serenzo TM is a natural ingredient used in food supplements.
Organic grade available
Manufactured in France
Stress manifestation decrease
Serenzo TM was evaluated in an open clinical trial for 12 weeks1. The efficacy was assessed using normative psychological questionnaires2 and a physiological marker. The first benefits were demonstrated after only 6 weeks:
50% reduction of subjective feeling of stress
53% reduction of global stress, measured through normative questionnaire
NEW - Improvement of Mood and Emotional well-being
In 2022, the new Serenzo™ consumer study conducted on 134 consumers showed a significant improvement on mental load and a significant boost of emotional well-being (assessed via DASS score variation) through time but not for placebo3,4.
A purified sea water extract
Source of marine minerals & micronutrients
Supports 10 health claims
Simag TM is a Natural Marine Magnesium.
It is a purified sea water extract and supports 10 health claims.
Magnesium is an essential mineral nutrient which plays a role in energy metabolism, mineral homeostasis, neuromuscular and endocrine functions. Thanks to Simag TM, Nexira offers a perfect solution to help fortify in magnesium.
Simag TM is a purified natural marine mineral extract. Its specific geographical origin allows a unique mineral profile. Gentle and solvent free process allows reduction of sodium and chloride content.
Magnesium is an essential nutrient and serves as a co-factor for over 300 enzymes involved in biological processes.
Nutritional and health claims:
Source of / rich in magnesium
EFSA scientific panel has approved 10 health claims for magnesium
Manufactured in France, Simag TM is a source of natural magnesium suitable for numerous applications thanks to its nutritional and health claims.
Improves muscle performance and break through the fatigue barrier
Powerful antioxydant
Amp up Nitric Oxide level
Improves muscle performance and break through the fatigue barrier
Powerful antioxydant
ViNitrox TM is a unique proprietary synergistic combination of apple and grape polyphenols. ViNitrox TM is the result of the association of a unique “terroir” expertise and a specific process to meet with specific athletes demands, looking for natural dietary supplements.
Nexira’s Grape Extracts are mainly sourced from famous French vineyards and are carefully harvested and selected to offer the highest content in phenolic compounds. Active ingredients are extracted from seed, leaf, skin and shoot as each part of the vineyard is unique.
Nexira draws its know-how from its exceptional French heritage to offer the best combination of grapes and apples supported by a clinical study.
Healthy blood flow is linked to production of Nitric Oxide (NO) by an enzyme called eNOs (endothelial Nitric Oxyde synthase). In vitro1 and ex vivo2 studies show that Vinitrox TM increases eNOs activation by 43% and NO production by 24%.
The latest clinical study of Nexira was conducted on 50 athletes aged from 25 to 451. Results shows that athletes who took 500 mg per day of ViNitroxTM and making an intense effort, improve physical capacities:
Increases physical training time by 10%
Optimized physical capacities by delaying the fatigue barrier by 13%
It offers outstanding properties on sports nutrition, especially with an effect on performance improvement and an extension of the effort duration. An in vivo study shows protective properties3:
A decrease of 74% of oxidative stress
A minimum guaranteed ORAC value 6000µmol TEq/g
In our latest consumer study, 1/2 of the athletes agrees that ViNitroxTM contributes to a general decrease of fatigue and reduces pain during the trail running.
Manufactured in France, ViNitroxTM is a nutraceutical ingredient easy-to-use in tablets, capsules, gels, shots etc..
Acerola is traditionally used in Brazil to support energy and vitality. This ingredient is a natural superfood, rich in vitamin C.
Particularly rich in vitamin C, did you know there is 40 to 100 times more vitamin C in a glass of acerola juice than in a glass of orange juice?
Sourced in Brazil and carefully selected through a long-term supply chain partnership, our growing range of acerola extracts (Malpighia glabra L.) is manufactured in France in our own factory using a gentle process (water extraction and spray-drying in fine powder) to preserve the high vitamin C content.
Thanks to its high content of Vitamin C, acerola offers a large array of benefits:
Supports energy & vitality
Helps the immune system for body protection
Protects cells from oxidative damage
Considered as a superfruit
Baobab is referred to as the new valuable “Superfruit” for uses in Foods, Beverages and Dietary Supplements based on its unique nutritional profile.
With more than 120 years of roots in Africa, Nexira continues to branch out and present with its latest Organic Superfruit Powder. Our production of Baobab Pulp Powder uses only the fruit; so the trees themselves are undamaged. Thanks to our strong supplier partnerships, we only select the highest quality Baobab for our customers. Our Baobab Pulp Powder is all-natural, organic certified, minimally processed & perfectly suitable for clean labeling.
Scientific studies have highlighted the high nutritional content of baobab fruit pulp:
A considerable content of nutrients including fiber, minerals and vitamins1,2
Greater antioxidant activity than other superfruits such as: mango, orange, pomegranate, kiwi, bilberry, etc3,4,5
Nexira’s Baobab fruit pulp guarantees 45% fiber content.*
As a pure powder, Nexira’s Baobab is perfectly suitable with Clean Label. Nexira’s Organic Baobab Powder is compliant with authorized Novel Food ingredient and meets FDA GRAS status for Baobab dried fruit pulp.
Baobab is a natural ingredient used in functional Food & Beverage and food supplements.
Nexira’s Baobab Pulp Powder has a subtle flavor. With its slightly tangy taste and fruity notes, our Organic Baobab Pulp Powder will be perfect to pep up yogurts, ice-creams, chocolates, cereal bars, beverages, smoothies,… Request your application bulletin!
Guarana is a climbing liana with small red fruits found wild in the Amazon rain forest.
Legend holds that the guarana plant with black seeds surrounded with a white fruit pulp, comes from the eyes of little Indian who was sacrificed by the God of Darkness.
Sourced in Brazil, our growing range of Guarana extracts (9300Paullinia cupana Kunth) is all-natural, available in native and organic grade up to 8% of caffeine from the seed and available in standardized range from 1% to 22% of caffeine.
Extracts are manufactured in France in our own factory using a gentle process (water extraction and spray-drying) to preserve the high caffeine content. With a caffeine content 3 times higher than coffee, Guarana is the best natural energy booster!
Thanks to its high content of caffeine, Guarana has many properties:
Evidence of longstanding use for fatigue and sensation of weakness
Contributes to improve physical and sport performance
Fat burner (increased thermogenesis), helps stave off hunger
Supports alertness, reduces mental fatigue
Guarana is a natural ingredient used in food (especially in soft drinks, energy drinks & sports nutritional products) and in food supplements.
Manufactured in France
Clean Label solution for natural caffeine enrichment
Suitable for vegetarian and vegan diets
USDA Organic available
Kosher Certified
Native color
