Clean & Care

  • Hepatoprotective Effect: Detox Boosting
  • Synergistic Antioxidant Activity in Liver Cells
  • Nutrigenomic Mechanism: Activation of Cell Defenses & Detoxification Pathway

Hepure is an organic and synergistic formulation of Clove and Immortelle extracts for a hepatoprotective and detoxifying action.


Immortelle (Helichrysum italicum), which comes from the rocky and sunny lands of the Corsican maquis in France, is also called Everlasting thanks to its exceptional longevity: its flowers never fade. Immortelle has been described in the literature for its antioxidant activity and its inflammatory marker modulation. 1,2,3

Clove (Syzygium aromaticum) has demonstrated its superiority in flavonoids content, antioxidant activity and its hepatoprotective effect. 4,5

Detox is a natural process that enables the neutralization and elimination of toxins. Liver allows the elimination of waste by transforming toxins and by a solubilization process, which require potent enzymatic cascade and can generate free radicals. Supporting antioxidant mechanism of the liver may be beneficial for detoxification process and hepatoprotection.

Starting with more than 100 botanical sources, Nexira compared antioxidant potency and nutrigenomic mechanism in liver cells through an extensive and innovative screening.

HEPURE has confirmed the best synergy in direct antioxidant activity and its superiority in increasing gene expression coding for antioxidant defenses by the liver cell (nutrigenomic mechanism). Thus, Hepure has proven a synergistic antioxidant activity in liver cells, the liver protection, a boost in antioxidant production, and a support to the detoxifying process.

Pending claim on Helichrysum italicum*: «Helps to maintain a healthy liver function, supporting the digestion and the body purification».

A detox cure can help contribute to digestive well-being, preserve the skin’s beauty, assist with weight loss, maintain energy and vitality, and strengthen the immune system.


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1. Monograph from Leung’s Encyclopedia, 3rd edition 2010 / 2. Benites, 2010 / 3. Redzic, 2007 / 4. Wojdylo 2007 / 5. Kazi 2016 ; Shyamala 2003 ; Adefagha 2014 ; Mammen 2018 ; Prasad 2010 ; El-Hadary 2016
*EFSA Pending Claim ID3771
This communication is not intended to the final consumer. It provides scientific information for professionals only. Communications to the final consumer have to be checked according to local regulations in force, since the conditions of use are beyond our control. This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.