In order to meet the requirements of an increasingly demanding market when it comes to efficiency and innovation, Nexira has conducted extensive research work in the field of weight management and offers a comprehensive range of healthy ingredients originating from diverse natural sources.
METABOLIC HEALTH ACTIVATOR
Premium
inavea CINNAMON ACACIA
Metabolic Health Activator
Glycemia & Insulinemia improvement
Demonstrated Prebiotic Activity
Carbon neutral, organic
inavea™ CINNAMON ACACIA is an all-natural and organic synergistic formulation of Cinnamon & Acacia, two African treasures with a long history within Nexira’s portfolio.
Providing prebiotic fibers from Acacia and polyphenols (including PACs) from Cinnamon, inavea™ CINNAMON ACACIA perfectly illustrates Nexira’s expertise in microbiome modulation.
In a recent in vivo study mimicking the conditions of dysbiosis-induced by a high fat high sucrose (HFHS) diet, inavea™ CINNAMON ACACIA has proven a strong prebiotic activity, a synergistic contribution to balance the gut microbiome and a significant role in metabolic heath improvement.
Our study has demonstrated the complementary & significant prebiotic activity of inavea™ CINNAMON ACACIA:
• Significant ability to modulate overall gut microbiota population
• Increase of SCFA propionate and butyrate production (1)
• Promotion of beneficial bacteria, such as Parabacteroides distasonis, which benefits on metabolic health markers such as glycemia and
weight have been substantiated (Wang et al, 2019)
inavea TM CINNAMON ACACIA is suitable in a wide range of dietary supplement applications and functional food & beverages:
[applications]
100 % all-natural & appealing combination
Subtle taste of Cinnamon
High fiber content**
Carbon neutral footprint
Nutrigenomic Mechanism: Activation of Cell Defenses & Detoxification Pathway
Hepure is an organic and synergistic formulation of Clove and Immortelle extracts for a hepatoprotective and detoxifying action.
Immortelle (Helichrysum italicum), which comes from the rocky and sunny lands of the Corsican maquis in France, is also called Everlasting thanks to its exceptional longevity: its flowers never fade. Immortelle has been described in the literature for its antioxidant activity and its inflammatory marker modulation. 1,2,3
Clove (Syzygium aromaticum) has demonstrated its superiority in flavonoids content, antioxidant activity and its hepatoprotective effect. 4,5
Detox is a natural process that enables the neutralization and elimination of toxins. Liver allows the elimination of waste by transforming toxins and by a solubilization process, which require potent enzymatic cascade and can generate free radicals. Supporting antioxidant mechanism of the liver may be beneficial for detoxification process and hepatoprotection.
Starting with more than 100 botanical sources, Nexira compared antioxidant potency and nutrigenomic mechanism in liver cells through an extensive and innovative screening.
HEPURE has confirmed the best synergy in direct antioxidant activity and its superiority in increasing gene expression coding for antioxidant defenses by the liver cell (nutrigenomic mechanism). Thus, Hepure has proven a synergistic antioxidant activity in liver cells, the liver protection, a boost in antioxidant production, and a support to the detoxifying process.
Pending claim on Helichrysum italicum*: «Helps to maintain a healthy liver function, supporting the digestion and the body purification».
A detox cure can help contribute to digestive well-being, preserve the skin’s beauty, assist with weight loss, maintain energy and vitality, and strengthen the immune system.
Synergistic complex for Appetite control
- Latest innovation for appetite control
- Unique synergistic combination
- Patent-pending formulation
Carolean™, a synergistic formulation based on carob and nopal, is a proprietary patent-pending complex specifically designed for appetite control.
Sourcing
With over 20 years of experience and unrivalled expertise on sourcing and processing, Nexira has established a leading position with its star ingredient: Cactus on the weight management market.
Nexira has acquired a Swiss company, expert in carob processing. Carolean™ complex is the fruit of combined R&D efforts to design an innovative solution.
Carolean™ provides both effectiveness and convenience for appetite control. The new patent-pending ingredient has demonstrated a clear ability to reduce appetite and limit cravings.
In conditions mimicking the ingestion (Temperature, pH), Carolean™ shows a superior kinetic reaching the satiety culmination quicker when compared to recognized market standards. 15 minutes after ingestion, already 70% of the viscosity is reached which optimizes the satiety effect more rapidly.
Our unique proprietary process enables a large variety of powder quality and behavior which makes our complex notably effective at ambient temperature.
Carolean™ is suitable for food supplements.
Cactinea is a weight management ingredient derived from the cactus fruit of Opuntia ficus-indica, called prickly pear.
Nexira and Tunisian farmers maintain a long-term partnership which respects both organic rules and sustainable farming. Direct sourcing includes rigorous selection and gentle process. With almost 20 years of experience and unrivalled know-how on cactus, Nexira delivers a high-performance cactus fruit extract.
The prickly pear is considered as a superfruit. It is an extremely potent antioxidant with proven metabolic health benefits on cholesterol modulation, vascular oxidative status and inflammatory markers modulation1,2,3.
Traditionally, prickly pear infusions are known for their depurative and diuretic benefits4,5. Cactinea TM has clinically demonstrated exceptional water elimination properties.6
Cactinea TM has also proven its efficacy by improving body shape and reducing heavy leg and swollen sensations.
Cactinea TM is a nutraceutical ingredient used in functional beverages and food supplements.
Organic grade available
100% Soluble & Clear in solution
Microgranulated powder
Natural carrier: acacia gum
Beautiful color (pink to orange)
Exotic taste
VinOgrape™ Plus is a natural grape extract with proven prebiotic effect and acting on microbiome modulation.
Our range of Grape extracts results from the association of an exceptional “terroir” with thousands of years of agricultural expertise & specific extraction process. VinOgrape™ Plus is produced using a special making process which provides the highest level of total polyphenols.
The International Scientific Association for Probiotics and Prebiotics (ISAPP) defines a prebiotic as ‘a substrate that is selectively utilized by host microorganisms conferring a health benefit’1 and has officially recognized grape extract as a prebiotic.
A 5-weeks in vivo study on intestinal mucosa markers and fecal microbiota in induced gut dysbiosis conditions shows that VinOgrape™ Plus significantly modulates the gut microbiota profile vs control after gut dysbiosis induction.
VinOgrape™ Plus has shown a significant ability to increase the abundance of Akkermansia muciniphila, suggesting an active role in metabolic disorder as well as weight control.
VinOgrape™ Plus is suitable for food supplements.
ID-alG TM is a brown seaweed extract derived from Ascophyllum nodosum and intended to help limit fat and sugar storage in the body and control weight.
Ascophyllum nodosum is a species of brown algae belonging to the Fucaceae family. It is often found along the rocky coasts of the North Atlantic, where it forms dense colonies. Measuring up to 1 meter 50, it is harvested manually all year round. After being carefully selected in the ocean, the long brown algae fronds are checked again in the local factory before the first processing stages.
Rich in marine polyphenols content that blocks the activity of the two main digestive enzymes, lipase and amylase, ID-alGTM is a weight-loss solution for women and more specifically for 45 years & over.
Thanks to its potent inhibition activity on lipases and on alpha-amylases, ID-alGTM reduces fats and carbs assimilation, inducing a reduction of the caloric intake for a global weight control effect. This inhibition activity of theses enzymes is guaranteed to overpass 50% (in tubo test).
The latest clinical study1 conducted with ID-alGTM confirms its outstanding weight management properties:
Significant weight loss correlated with fat mass
Decrease in fat assimilation lowering body fat mass and abdominal & visceral fat
Significant reduction in carbs assimilation, leading to a decrease in glycated hemoglobin (HbA1C)
Body shape improvement
No signs of discomfort
Nexira delivers a high-performance ingredient in weight management, approved by the general satisfaction of consumers2:
76% were convince of the weight management effect of ID-alG™
72% would continue using ID-alG™
ID-alG TM is a natural ingredient manufactured in France, used in food supplements.
Okralin TM is a 100% natural and patented fat binder for weight management, formulated with okra and inulin.
Okra is one of the oldest cultivated crops. Well-known, Okra is usually consumed as a vegetable in salad, soup or stew.
Nexira has full control over our supply of okra, from seed selection to final powder.
Grown in our partner plantations, the okra pods are carefully selected, hand-picked and gently processed into a fine powder.
Shipped to our manufacturing facilities in France, the okra is processed to obtain the exclusive and patented ingredient with a proprietary formulation we call OkralinTM.
Manufactured in France, 100% natural and vegan, Okralin TM has been awarded by NIE Magazine ingredient of the Year in the “Weight Maintenance” Category. The jury declared “Nexira has brought to market a product with the whole package: fully traceability, renewable plant-based source, preclinical and clinical data with meaningful endpoints. This is exactly the kind of ingredient the space needs to continue to build credibility and trust with consumers.
OkralinTM , the breakthrough fat binder, is the newest and the most powerful fat binder on the market.
Acting in the stomach, OkralinTM binds fats. The complex creates a gel that is naturally eliminated, reducing fat and calorie absorption.
Supported by a 12-week clinical study, strongly documented, OkralinTM showed amazing results on weight-loss for men and women, losing 4 times much weight than those on a healthy diet alone.
Acting on body fat mass reduction, hip and waist, 97% of consumers were satisfied by benefits.
The clinical study strengthens the impressive benefits and tolerability of OkralinTM.
OkralinTM is a nutraceutical ingredient used in food supplements.
Neopuntia TM is a natural weight management pure cactus powder. Neopuntia TM is a patented combination of insoluble and soluble dietary fibers.
Nexira and Tunisian farmers maintain a long-term partnership which respects both organic rules and sustainable harvesting of Opuntia ficus indica. Through its cactus sourcing, Nexira is involved in sustainable development via environmental, human and economic actions.
With over 20 years of experience and unrivalled expertise on cactus sourcing and processing, Nexira offers a standardized pure cactus leaf powder. Neopuntia TM is perfect for nutraceutical applications.
In vitro1 study, simulating gastrointestinal tract conditions, has demonstrated a reduction of fat absorption: 28% of ingested fat binds to Neopuntia TM while branded chitosan showed no effect.
A pilot clinical study2 has also demonstrated results on human: Neopuntia TM increases fat excretion by 27%.
Neopuntia TM absorbs fat and sugar3 and supports healthy weight management.
A published clinical study4 shows Neopuntia TM, consumed with a healthy diet, has positive effects on balancing blood lipids levels. Neopuntia TM helps to increase HDL cholesterol level.
39% of women studied no longer showed Syndrome X criteria using Neopuntia TM.
Three interventional studies in human demonstrated positive and significant glycaemia modulation5,6,7.
Neopuntia TM is a nutraceutical ingredient used in supplements and functional food.
Organic grade available
Pure cactus powder
